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ReMedium Silk Exosome Hair Filler
ReMedium Silk Exosome Hair Filler
Regular price
€49,00
Regular price
€65,00
Sale price
€49,00
Unit price
/
per
Taxes included.
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scalp aging and hair loss
Alopecia and other hair abnormalities can have various causes. The most common are:- Loss of collagen in hair follicles due to aging;
- Loss of capillaries in the scalp, which interrupts the supply of oxygen and nutrients to the follicles;
- Reduction in follicle size and increased oil production due to DHT hormone expression;
- Reduced regeneration and healing ability of the scalp due to a compromised skin barrier;
- Reduced pigment transport due to loss of melanocytes (grey hair).
This is what scalp aging looks like
Healthy scalp

stem cells

Damaged scalp

main ingredient
ASC exosomes
Exosomes are tiny extracellular vesicles, approximately 100 nanometers in size. They are the primary mechanism of cell-to-cell communication in our body, acting as messengers that deliver lipids, proteins, and RNA that activate biological responses in recipient cells.

Pure stem cell-exosome composition

complexity size
Benefits of Exosomes
1. Anti-inflammatory effect Exosomes play an important role in relieving inflammation by transporting the enzymes needed to produce extracellular adenosine, a powerful anti-inflammatory agent that regulates immune activity and subsequently prevents excessive inflammation in the scalp and hair follicles. 2. Promoting the structural components of the skin barrier Exosomes promote the synthesis of important components of the skin barrier – sphingolipids. These are important molecules of the epidermis that intervene in the modulation of our skin cells. They are involved in ceramide production, the proliferation and differentiation of keratinocytes, as well as the production of an important epidermal immune element (CAMP), maintaining the health of the skin barrier.Anti-inflammatory effect of exosomes on the scalp

ExoSCRT™ isolation technology
The traditional method for isolating and purifying exosomes has been ultracentrifugation. However, this method always results in some degree of destruction of exosomes. For this reason, Silk Exosome Hair Filll's exosomes are isolated using ExoSCRT™, a novel patented filter technology that successfully preserves the quality of each individual exosome.

active ingredient
01 Biotinoyl Tripeptide-1
Biotin Tripeptide-1 is a three-amino acid peptide that combines the famous collagen fragment GHK with biotin, a well-known dietary supplement for stronger hair and nails. The resulting Biotinoyl Tripeptide-1 has shown an effect on hair growth comparable to minoxidil.Benefits of Biotinoyl Tripeptide-1
1. Hair cell activation Promotes keratinocyte proliferation at the follicle base and supports optimal hair anchorage by stimulating the synthesis of adhesion molecules – laminin 5 and collagen IV. This results in stronger hair that stays in place longer. 2. Stimulation of gene expression Stimulates the expression of the Ki-67 gene, a proliferation marker protein associated with cell proliferation as well as tissue regeneration and supports the restoration of damaged hair follicles. 3. Regulation of hair cell metabolism Promotes scalp microcirculation and stimulates cell communication, improving the supply of oxygen and nutrients to hair follicles. This reduces hair follicle atrophy and signs of scalp aging.
- Similar effect at the same concentration (2 ppm)
- Significant increase in hair production at higher concentration (5 ppm)
- No irritation or side effects at the recommended dosage
02 Copper tripeptide-1
Copper Tripeptide-1 (GHK-Cu) is a copper peptide complex that occurs naturally in body fluids such as plasma and saliva. Since copper deficiency is one of the causes of signs of skin aging and hair loss, this tripeptide is quickly becoming a popular ingredient in hair and scalp treatments.Benefits of Copper Tripeptide-1
1. Hair Follicle Enlargement When studying the wound healing properties of GHK-Cu, an enlargement of hair follicles in the area was observed, which eventually led to the discovery that copper peptides stimulate hair growth by stimulating follicle cell proliferation, resulting in larger follicles that produce longer and thicker hair. 2. Hair Growth Cycle Regulation Copper peptides stimulate and lengthen the hair growth phase (anagen), resulting in more time for active hair growth and thicker hair strands. They are also involved in shortening the inactive phase of hair follicles (telogen), reducing hair loss and preventing premature follicle death. 3. DHT Hormone Inhibition Dihydrotestosterone (DHT), a hormone converted from testosterone, is the main cause of androgenetic hair loss. DHT is converted thanks to an enzyme called 5-alpha reductase, which has been shown to be blocked by peptides. In this way, copper peptides block DHT production and prevent further hair loss.03 Polypeptid
1. sh-polypeptide-1 (FGF2) Synthesized copy of the human gene encoding basic fibroblast growth factor (FGF2). Stimulates the growth and proliferation of fibroblasts and keratinocytes, as well as the synthesis of collagen and other extracellular matrix components, and promotes skin barrier health. 2. sh-polypeptide-4 (SCF) Synthesized copy of the human gene encoding stem cell factor (SCF). Plays an important role in the formation of blood cells and melanocytes, and regulates the survival and proliferation of adult melanocytes to maintain normal pigment transport (prevention of gray hair). 3. sh-polypeptide-12 (NOG) Synthesized copy of the human gene encoding noggin protein (NOG). Noggin is a signaling molecule that plays a role in tissue development and the derivation of specialized cells. Studies show that Noggin signaling is required for the initiation of the hair follicle growth phase (anagen).Silk Exosome Hair Filler and the Hair Growth Cycle
Biotin Tripeptide-1 is a three-amino acid peptide that combines the famous collagen fragment GHK with biotin, a well-known supplement for stronger hair and nails. The resulting biotinoyl tripeptide-1 has shown comparable effects to minoxidil in hair growth.
Results of the case study on silk exosome hair fillers


introductions to the application
1. Shampoo Wash scalp and hair with Silk Exosome Hair Filler Shampoo. 2. Exfoliate Remove harmful environmental factors that clog pores, such as dead skin cells, sebum, dandruff and other impurities that remain on the scalp. 3. Silk Exosome Hair Fill & MTS- Divide the scalp into sections and apply the Remedium Exosome Hair Filler ampoule. – MTS: Roll over each section in a vertical-horizontal-diagonal pattern and repeat 5 to 10 times.
- needle (33G)
TIPS
- Pain care
- MTS depth
- Needle 0.5-1.2mm 33G
- Hair loss management
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